Choice of peritoneal dialysis over other renal replacement therapy modalities for adult critically ill patients is still limited; despite the data against it. The present article presents a case of peritoneal dialysis in a patient with intracerebral hemmorhage and reviews the relevant literature. Continue reading
Sickle cell disease (SCD) is an umbrella term that defines a group of inherited diseases (in-cluding sickle cell anaemia (SCA), HbSC and HbSβ-thalassaemia) characterized by mutations in the gene encoding the haemoglobin subunit β1
. One of the most frequent and debilitant complications of the disease is the vaso-occlusive crisis (VOC), which is mediated by multicell adhesion between red blood cells (RBCs), white blood cells, platelets, and endo-thelial cells and causes intense pain in conse-quence of impaired oxygen supply, but also in-farction-reperfusion injury2,3
. Continue reading
Death is the reason for the existence of resuscitation. The Western definition of death has evolved continuously over the last three centuries. Today, the world recognizes two types of biological death: cardiac or “real” death (I,e. definitive cease of cardiac , respiratory and cerebral function) and encephalic death. The latter (brain death) has been accepted worldwide medically and legally as the biological state of death of the organism. Continue reading
is a Gram-negative, oxidase-negative, aerobic that belongs to Enterobacteriaceae family and has a lot of similarities with Klebsiella spp.
Though initially rare mentioned as an opportunistic infection, more and more reports are published. In the present article we present a case of an R. planticolla
upper respiratory infection and we review the relevant literature. Continue reading
Subcutaneous emphysema (SE) refers to air in the subcutaneous tissues. Clinical manifestation is generally benign, yet in several cases it can provoke serious complications such as airway compromise, respiratory failure, pacemaker malfunction and tension phenomena.
Treatment is usually aiming at the underlined cause, while the air is gradually absorbed from interstitial tissues. However, in extensive cases, surgical intervention may also needed1
. In the present article we present a case report of subcutaneous emphysema in patient with COVID-19 with presence of ginko leaf sign. Continue reading
COVID-19 has brought up the interest about hyperferritinemic syndromes. Though often seen in COVID-19, especially within the frame of COVID-CSS, hyperferritinemia needs a systematic diagnostic approach, as co-infections or other causes may also increase ferritin. In this article, we present a case report of extreme hyperferrinemia in an male criticall ill patient with COVID-19 and we perform a short synthesis of the available literature. Continue reading
Therapy armamentarium for multpile sclerosis include a variety of drugs. Natalizumab, a humanized antibody, is widely used in relapsing-remissing multiple sclerosis. Anticonvulsants, like topiramate, are also widely used for symptomatic relief. We hereby describe a case of Status epilepticus and topiramate induced metabolic acidosis in a female patient with multiple sclerosis under natalizumab therapy. Continue reading
Respiratory failure due to Coronavirus 2019 (COVID-19) disease has triggered a debate about when and how to apply mechanical ventilation in these patients, as it has been proposed that severe "atypical" ARDS of COVID-19 cause an ARDS pandemic. As global database grows, it is evident that about 6% of patients will need admission to the ICU. About 75% of these will require invasive ventilation, and approximately 10% will need ventilation beyond 14 days. Different ventilation strategies are followed yet there is no strong evidence in favor of anyone. The present article attempts to gather the daily evolving evidence on the subject. Continue reading
Patient care in Intensive Care Units is characterized be high demanding tasks, which lead in daily high workload. In the present study, a questionnaire-based evaluation of ICU nurse’s workload was conducted at the adult general 7 - beds ICU of a small urban hospital. NASA Task Load Index (TLX) along with other two tools, used for the first time in healthcare environment: Instantaneous Self-Assessment (ISA) and Crew Status Survey (CSS) were used for that purpose. Information about every nurse’s professional background and basic demographics were also collected. Responses from 70% of total nurse staff were collected. Continue reading
Hemophagocytic Lymphohistiocytosis (HLH) is a life-threatening syndrome of excessive immune activation that mostly occurs as primary (hereditary) disease in children. Acquired HLH is associated with infections, cancer of rheumatological conditions. Both are rare in adults. Turicella otitidis is a bacterium, that is associated with ear infections and there is only one case report of bacteraemia. The present report describes a case of acquired HLH with invasive pulmonary Aspergillosis and Turicella otitidis bacteraemia in an adult patient; and also reviews the relative literature. In conclusion though rare, acquired HLH is a devastating condition that clinicians should have in mind when managing patients with multiple infection or underlying immunosuppression. Continue reading