At 2012 the ICU of General Hospital of Trikala has registered as CAF user in the CAF database. With this quality management instrument, public sector organizations improve their performance by recognizing weaknesses and by promoting strong points. The purpose of using CAF protocols is to improve the quality of provided Health services. For the implementation of CAF we used specialized questionnaires such as: CAF questionnaire, family satisfaction (FS- ICU 24), questionnaire concerning nursing care (TISS - 28) and about fatique of personnel (Burn-out questionnaire). Also, indicators such as observations of mortality in relationship with the cost (SMR/SRU), Bacteraemias, V.A.P (Ventillation associated pneumonia), and the effectiveness of nurse project (Level of ICU) have been used. The design of CAF protocol implementation was adjusted, as structure, according to the data of our ICU. General Indicators concerning Public sector administration have been used but also specialized indicators concerning ICU output, mortality rate, infections and cost. Undergoing this project by using the CAF quality instrument the target is to identify fields were effective functioning was observed (strong points) and fields that need improvement (weak points). The purpose is, throughout self assesment evaluation but also with Bench-marking with other ICUs, to improve the provided health services from the ICU of General Hospital of Trikala.