Intrathecal drug administration extends beyond the purposes of anaesthesia, to therapeutic applications. Here, we describe the case of a patient with severe Systemic Lupus Erythematosus having affected multiple organs and had a meningococcal infection. She was treated with intrathecal antibiotic therapy resulting in a successful outcome.

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The scope of this study was to investigate if changing the direction of the Whitacre 26G needle aperture in regional anaesthesia during planned caesarean section produces a difference in the dose-response curves of the level of subdural blockade achieved by ropivacaine 0.75% and a standard dose of opioid. One hundred and twenty healthy parturients were blindly randomised in two groups, with 5 subgroups of 12 women each.

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We have assessed intubating conditions and haemodynamic changes in three groups of 30 ASA I or II patients after induction of anaesthesia with propofol 2 mg*kg-1, remifentanil 0.5 μg*Kgr-1 and rocuronium 0,6 mg*kg-1 (group R), propofol 2 mg*kg-1 and remifentanil 1.5 μg*Kgr-1 (group F) and propofol 2 mg*kg-1, remifentanil 1.5 μg*Kgr-1 and midazolam 0.015 mg*kg-1 (group M).

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