The objective of this study was to evaluate onset times and tracheal intubating conditions after administration of rocuronium or mivacurium in children of different ages. In this randomized double-blind study, 40 healthy (ASA I) children aged 1 to 14 years were studied. They were divided, according to age, into two groups: Group A (n=20) included patients 1 to 3 years of age and Group B (n=20) 4 to 14 years of age. After general anesthesia induction patients in both groups were further divided into two subgroups.

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In order to evaluate the postoperative analgesic effect of caudal administration of levobupivacaine, plain or in combination with neostigmine, 50 children who underwent medium gravity operations were studied. The children were randomly divided into two groups: Group L received 1 ml/kg of levobupivacaine 0.25% solution via caudal route, while in Group LN the same solution plus 2 μg/kg neostigmine was given.

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Atropine has been used in the past as a premedication drug to decrease the sialorrhea of the second stage of anaesthesia and prevent bradycardia caused by the administration of succinylcholine, opiods or volatile anaesthetics. The purpose of this study is the investigation of the haemodynamic fluctuations during induction of anaesthesia and intubation of the trachea, in children and adults either premedicated or not with atropine.

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