Perioperative anaphylaxis is a rare but potentially life-threatening event requiring rapid recognition and immediate intervention. Neuromuscular blocking agents (NMBAs) remain among the most common culprits, with rocuronium being a frequent trigger. This report presents a case of severe anaphylaxis during anesthesia induction, followed by a second uneventful anesthetic exposure after modification of the anesthetic approach. Continue reading
This case report focuses on the anesthetic management of a patient with Myasthenia Gravis who underwent left-sided colectomy, due to the presence of a tumor on the left colic (splenic) flexure. Myasthenia gravis is a chronic autoimmune neuromuscular disease which is characterized by differ-ent degrees of weakness of skeletal muscles. The anesthetic management and treatment of every patient with myasthenia gravis should be performed carefully, due to the fact that many periopera-tive complications may occur. In our case anesthetic technique included the combination of general anesthesia, with the use of neuromuscular agent and thoracic epidural blockade with the use of a catheter, which permitted intermittent boluses doses and continuous infusion of local anesthetics and opioids. Neuromuscular blockade was reversed with the use of sugammadex. Patient’s periop-erative management was effective and uneventful.
Continue readingThe objective of this study was to evaluate onset times and tracheal intubating conditions after administration of rocuronium or mivacurium in children of different ages. In this randomized double-blind study, 40 healthy (ASA I) children aged 1 to 14 years were studied. They were divided, according to age, into two groups: Group A (n=20) included patients 1 to 3 years of age and Group B (n=20) 4 to 14 years of age. After general anesthesia induction patients in both groups were further divided into two subgroups.
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