General anaesthesia is associated with a reduction in heart rate variability (HRV) compared to awake situation. In this study the hypothesis of reduction in HRV was tested in two different levels of anaesthesia depth. Forty six patients were randomly allocated in two groups, where anaesthesia was maintained with sevoflurane (n=23) or propofol (n=23). Administration of both anaesthetics was regulated in order to achieve a BIS value 25±5, followed by an increase to 55±5, both being stable for 5 min.
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