Case Reports

Acquired hemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies to coagulation factor VIII (FVIII) leading to potentially severe bleeding diathesis that carries a high rate of morbidity and mortality. It should be suspected in patients with unexplained prolonged aPTT, normal PT and acute abnormal bleedings without personal or familiar history of congenital bleeding disorders. Continue reading
Myasthenia Gravis (MG) is an autoimmune disorder affecting the neuromuscular junction function and causing muscle weakness that gets worse during the day and after physical activity. The most common medication prescribed for MG treatment is pyridostigmine. Continue reading
Depth of anesthesia is a dynamic balance between effect-site concentration of hypnotic and analgesic drugs, and intensity of surgical stimulation. The bispectral monitor is the best described monitor of the depth of hypnosis component of anesthesia. Continue reading
Hypothyroidism is relatively common comorbidity in elderly patients, due to structural and hormonal changes in the aging thyroid. Diagnosis of hypothyroidism, in this population, is considered challenging, since many symptoms are nonspecific and may be attributed to other common medical conditions. Continue reading
Aortic aneurysms occur mainly due to atherosclerotic disease, and their conventional surgical repair is reserved for patients with anatomy unfavorable to endovascular repair. In this context, one of the challenges for the anesthesiologist is perioperative anesthetic-analgesic control. Continue reading
Nitrous oxide, also known as “laughing gas”, has been used for more than 150 years in medical practice, autonomously or in combination with other inhalation anesthetics, for pain relief, in various surgical interventions. In modern medicine, its use has declined, due to its side effects and also because of the advent of newer, shorter-acting agents and newer inhaled anesthetics. Continue reading
Orthotopic liver transplantation (OLT) has become a relatively safe procedure over the last decades, with reported 5-year survival rate of over 80%.    Increasing numbers of patients will be transplated at a younger age and they will seek obstetric anaesthesia services, as their fertility is restored after succesful transplantation. In 1978, the first succesful pregnancy was reported. Continue reading
Graft-versus-host obstructive bronchiolitis, in pediatric patients, is a relatively common respiratory complication of chronic graft-versus-host disease, after allogeneic bone marrow transplant. It is irreversible, chronic and potentially life-threatening condition. Continue reading
Despite the vast progress in contemporary medicine, the burden of spinal cord injury has increased over the last decades. Thus, more and more often patients with paraplegia appear for an emergency or elective surgery below the level of the injury. Anesthetic management of those patients can be turn out to be a challenge. Continue reading
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