2022

• LETTER FROM THE EDITORS.
• CLINICAL IMPACT OF MEDICAL CANNABIS ON PATIENTS WITH SICKLE CELL DISEASE PAIN: A SCOPE REVIEW.
• RESUSCITATION MEDICINE AND DEATH DEFINITION.
• INTRAOPERATIVE HYPOXEMIA IN THORACIC SURGERY: IMPACT ON EARLY OUTCOME.
• CEASERIAN SECTION IN A PARTURIENT WITH BEHÇET'S DISEASE: CASE REPORT AND LITERATURE REVIEW.
• RAOULTELLA PLANTICOLA AN EMERGING PATHOGEN? CASE REPORT AND LITERATURE REVIEW.
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Dear colleagues,

The firs tissue of the Greek e-journal of Perioperative Medicine for 2022 presents a variety of scientific articles.

The systematic review article of Guimarães Pereira JE et al. presents the efficacy and safety of medicinal cannabis on clinical outcomes of patients suffering from sickle cell (SCD) anemia pain. Due to the lack of evidence in the current literature, the authors noted in their conclusion, the need for large RCTs in order to evaluate the impact of cannabis use among SCD patients on quality of life and also on the controversial association between cannabis use and an increase in Emergency Room visits.

Next, the article of Aslanidis Th et al. reviews the available literature about the possible need for a new definition of death due to the fact that the advance of resuscitation medicine (in intensive care units or not) profoundly modified the durations of agony and the survival times, and perhaps also the essential meaning of death.

The retrospective clinical study of Deligianni M et al. showed that hypoxia during one lung ventilation (OLV) did not have negative impact on early outcome in patients that underwent thoracic surgical procedures, on the precondition that there was  no underlying… Continue reading

Sickle cell disease (SCD) is an umbrella term that defines a group of inherited diseases (in-cluding sickle cell anaemia (SCA), HbSC and HbSβ-thalassaemia) characterized by mutations in the gene encoding the haemoglobin subunit β1. One of the most frequent and debilitant complications of the disease is the vaso-occlusive crisis (VOC), which is mediated by multicell adhesion between red blood cells (RBCs), white blood cells, platelets, and endo-thelial cells and causes intense pain in conse-quence of impaired oxygen supply, but also in-farction-reperfusion injury2,3. Continue reading
Death is the reason for the existence of resuscitation. The Western definition of death has evolved continuously over the last three centuries. Today, the world recognizes two types of biological death: cardiac or “real” death (I,e. definitive cease of cardiac , respiratory and cerebral function) and encephalic death. The latter (brain death) has been accepted worldwide medically and legally as the biological state of death of the organism. Continue reading
Anesthesia for thoracic surgery presents specific challenges since anesthesiologists have to manage patients with several comorbidities, apply One Lung Ventilation (OLV) to facilitate surgery and at the same time they should try to maintain adequate safe oxygen levels. Hypoxemia is a common consequence of OLV. The aim of the present retrospective study was to investigate the impact of intraoperative hypoxia on the early outcome of patients. Continue reading
Behçet’s Disease is a chronic autoimmune disorder manifesting mainly with mucocutaneous ulcers (mostly in the oral cavity and the genitalia), ophthalmic lesions and systemic vasculitis. Neuro-Behçet is a severe though rare form of the disease. Behçet’s Disease effect on pregnancy is controversial with higher rates of miscarriage, but with symptoms remission during peripartum period. Mouth scarring from ulcers can complicate general anesthesia rendering intubation impossible and neuro-Behçet’s CNS complications can avert general techniques. Here, we present the case of a C-section in a parturient with this uncommon disease and the anesthetic considerations. Literature review is also discussed. Continue reading
Raoultella planticola is a Gram-negative, oxidase-negative, aerobic that belongs to Enterobacteriaceae family and has a lot of similarities with Klebsiella spp. Though initially rare mentioned as an opportunistic infection, more and more reports are published. In the present article we present a case of an R. planticolla upper respiratory infection and we review the relevant literature. Continue reading
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