The aim of this study was to investigate the effects of a positional change of regional cerebral oxygen saturation values (rSO2) because of the sitting position, before and after the administration of general anaesthesia. Twenty five consecutive patients of ASA class I or II undergoing shoulder surgery under general anaesthesia were chosen to participate in this study.
Continue readingThe objective of this study was to evaluate onset times and tracheal intubating conditions after administration of rocuronium or mivacurium in children of different ages. In this randomized double-blind study, 40 healthy (ASA I) children aged 1 to 14 years were studied. They were divided, according to age, into two groups: Group A (n=20) included patients 1 to 3 years of age and Group B (n=20) 4 to 14 years of age. After general anesthesia induction patients in both groups were further divided into two subgroups.
Continue readingAiming the investigation of potential differences in accuracy of the algorithms of pediatric anesthesia in everyday practice, 338 children where studied, from newborns to 14 years old, who underwent scheduled or emergency operations in a 3 months period. They were divided according to their age into 4 groups (38 newborns and infants, 43 children from 1 to 3 years old, 90 children from 3 to 6 years old, 167 children >6 years old).
Continue readingGeneral anaesthesia is associated with a reduction in heart rate variability (HRV) compared to awake situation. In this study the hypothesis of reduction in HRV was tested in two different levels of anaesthesia depth. Forty six patients were randomly allocated in two groups, where anaesthesia was maintained with sevoflurane (n=23) or propofol (n=23). Administration of both anaesthetics was regulated in order to achieve a BIS value 25±5, followed by an increase to 55±5, both being stable for 5 min.
Continue readingIn order to evaluate the postoperative analgesic effect of caudal administration of levobupivacaine, plain or in combination with neostigmine, 50 children who underwent medium gravity operations were studied. The children were randomly divided into two groups: Group L received 1 ml/kg of levobupivacaine 0.25% solution via caudal route, while in Group LN the same solution plus 2 μg/kg neostigmine was given.
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This study was undertaken to investigate the efficacy of prehydration with crystalloids or colloids for preventing spinal anaesthesia-induced hypotension in elderly normotensive and hypertensive patients. Eighty physical status ASA I-III elderly patients were enrolled in this study, receiving spinal anesthesia.
Continue readingAcute inflammatory response is the body’s direct response to noxious stimuli or to tissue necrosis. Ischemia-reperfusion lesion is a clinical state of acute inflammation with leucocyte-induced tissue damage. Ischemia promotes an inflammatory response which sensitizes tissues to further damage during reperfusion. Reperfusion activates inflammatory mediators from remote vascular or tissue sites or from the local vascular bed. Reperfusion remains the cornerstone for the repair of ischemic areas.
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Atropine has been used in the past as a premedication drug to decrease the sialorrhea of the second stage of anaesthesia and prevent bradycardia caused by the administration of succinylcholine, opiods or volatile anaesthetics. The purpose of this study is the investigation of the haemodynamic fluctuations during induction of anaesthesia and intubation of the trachea, in children and adults either premedicated or not with atropine.
Continue readingPostoperative vomiting (PV) is a complication of surgery under general mainly anaesthesia. Nowadays about 1 in 3 surgical patients complain of PV. The aetiology of PV is multimodal and so must be the management. There are simple methods to predict the patients who will vomit postoperatively and these patients must be managed with special measures, preferably before PV will be established. Aetiology, prediction and management of high risk for PV patients are analyzed and discussed.
Continue readingThe aim of this study was to estimate the incidence of postoperative vomiting (POV) in patients undergoing operations under general anaesthesia, as well as the application of a simple risk score for prediction of POV. Four hundred thirty one patients scheduled to undergo four different kinds of surgical procedures under general anaesthesia (mastectomy, thyreoidectomy, abdominal hysterectomy, laparoscopic cholecystectomy) were included in the study.
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