The goal of this study is to examine and describe the methods and techniques, as well as the knowledge of the anatomy and treatment of venous pathology, and their influence on the birth of phlebology in ancient Greece and Byzantium.The study was conducted reviewing sources in Russian and foreign literary in Greek and in English language, which, in turn, allowed a detailed study of discoveries and treatment in the field of venous system anatomy. Conservative methods are also described, as well as the first vein surgeries, precursors of modern surgical interventions that were unique for that time and are still relevant today. Brief biographies and discoveries of scientists of those eras are also mentioned.
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