ABSTRACT
Patient’s rights mandate that every patient in chronic pain has the right to receive proper and effective treatment. It is widely acceptable that opioids can significantly improve the patient’s quality of life, irrespectable of the etiology of pain, either cancer or non-cancer. However, there is evidence that some patients receiving opioids for chronic non-cancer pain, not only fail to improve their quality of live, but end up with added, new difficulties, that are really hard to cope with. So there is a call for reasonable prescribing practice, which means that opioids should only be administered to those who will ultimately benefit, based on careful and thoughtful therapeutic approach.