The study of mechanisms by which drugs can modify cellular and ultimately whole animal and human performance is still one of the most exciting branches of science. However and despite the fact that many physicians are frequently using some times more than 20 drugs simultaneously in critically ill patients, very few of them are able to understand the enormous complexity and variability of different therapeutic responses within patients and/or between patients suffering from critical illness.
Continue readingThe management of cardiologic patients who are presenting for diagnostic and theurapeutic cardiac interventions has become a significant topic of interest and concern among anesthesiologists. This review will update recent reports and also will provide practical advice on delivering anesthesia in cardiac catheterization laboratory. During recent years cardiac procedures are more complex, take longer, and involve high risk patients.
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Despite of great interest in understanding the pain mechanisms and pain management, and the foundation of acute pain services; numbers of patients still suffer unacceptable pain even today. Surveys show that there are not many improvements in this area. So, it is quite clear that the solution to post operative pain is not just developing a single technique.
Continue readingDamage control surgery is defined as rapid termination of an operation after control of life threatening bleeding and contamination in severely injured and unstable patients, followed by correction of physiologic abnormalities and de-finitive management. Emphasis then shifts from the operating theater to the intensive care unit, where the patient’s physiologic deficits are corrected.
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Apneic oxygenation is an adjunct „ventilation‟ technique that involves insufflation of oxygen at varying flows through a catheter that is inserted through the endotra-cheal tube and is positioned above the carina. Apneic oxygenation improves gas exchange efficiency and preserves the arterial oxygenation at an acceptable level.
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A lot of techniques have been tested for their potential to salvage myocardial tissue during an episode of acute ischaemia. Techniques that are applied before the onset of acute ischaemia, i.e. preconditioning techniques, have proved to be really protective, but scheduled ischaemia or at least high probability for the timing of it’s occurrence, is a pre-requisite for their application. This disadvantage led to experimentation on techniques that can be applied immediately after the onset of acute ischaemia or at least on the time of reperfusion.
Continue readingEarly tracheal extubation has been safely performed after large operative procedures, questioning the need for routine postoperative ventilation. Because immediate postoperative tracheal extubation of liver transplanted patients has not been previously reported in Greece, we announce the first case report.
Continue readingΕκτίμηση της εγκεφαλικής αυτορρύθμισης με τη χρήση του διακρανιακού Doppler (TCD) και καθοδήγηση της θεραπείας σε ασθενείς με σοβαρή κρανιοεγκεφαλική κάκωση
Φαρμακολογία του Βαρέως Πάσχοντα Ασθενή (Μέρος Ι). Αρχές Φαρμακοκινητικής και Μεταβολές της στη Βαριά Νόσο
Management of intraoperative fluid balance and blood conservation in adult cardiac surgery
Αναισθησία για μη καρδιοχειρουργικές επεμβάσεις σε ασθενείς με διαδερμική αγγειοπλαστική των στεφανιαίων με ή χωρίς ενδοπροθέσεις (stents)
Ηθικά διλήμματα, προτελεύτιες αποφάσεις και αποκλιμάκωση θεραπείας στη Μ.Ε.Θ.
Κλινική μελέτη σύγκρισης των λαρυγγοσκοπικών εικόνων που προκύπτουν με τη χρήση video laryngoscope ή συμβατικού λαρυγγοσκόπιου
Η καθιστική θέση υπό γενική αναισθησία προκαλεί μείωση των τιμών της εγκεφαλικής οξυγονομετρίας
Ενδονοσοκομειακά επείγοντα περιστατικά: Ιατρικές ομάδες άμεσης αντιμετώπισης βασισμένες σε αναισθησιολόγους
Τεχνικές υποβοήθησης της ινοπτικά καθοδηγούμενης στοματοτραχειακής διασωλήνωσης υπό γενική αναισθησία. Υπάρχει υπεροχή κάποιας τεχνικής;
Combination of transdermal fentanyl with codeine or tramadol for the management of severe cancer pain
Κατεύθυνσης της οπής της υπαραχνοειδούς βελόνης Whitacre 26G και επίπεδο του αισθητικού αποκλεισμού της ροπιβακαΐνης 0,75% σε επεμβάσεις Καισαρικής Τομής
Placenta percreta with bladder involvement and profound haemorrhage: a report of two cases and short review of the literature
ΑΛΛΗΛΟΓΡΑΦΙA – «Περί διασωλήνωσης της τραχείας και περί του αντιθέτου».
A majority of current pharmacokinetic and pharmacodynamic data are generated from studies in healthy volunteers and stable patients with single organ dysfunction. However, critically ill patients differ from other patients because of the complex and unstable nature of their illness. Critical illness results in multiple changes that alter drug disposition in the body. As organs fail, so the pharmacokinetic processes of absorption, distribution, and elimination are affected.
Continue readingThe ability of the cerebral vascular bed to undergo constriction or dilation in response to various stimuli is termed vascular reactivity or cerebral autoregulation. When the stimulus is the change in cerebral perfusion pressure (CPP) the vascular response is termed cerebrovascular pressure reactivity. When the stimulus is the change in PaCO2 the vascular response is termed carbon dioxide reactivity. The transcranial Doppler (TCD) provides information about changes in flow velocities secondary to changes in CPP or PaCO2.
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