Anaphylaxis is a severe, potential life threatening allergic reaction, which is characterized by rapid onset and varied clinical manifestations involving in most of the cases the respiratory and cardiovascular systems and sometimes skin and mucosa. Twentysix patients (16♀ & 10♂) with a mean age of 59.7± 8.6yrs were included in this study. Continue reading
Despite the vast progress in contemporary medicine, the burden of spinal cord injury has increased over the last decades. Thus, more and more often patients with paraplegia appear for an emergency or elective surgery below the level of the injury. Anesthetic management of those patients can be turn out to be a challenge. Continue reading
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis characterized by progressive ossification of the spinal column with resultant stiffness. Patients, with AS, have a suppressed immune function due to proinflammatory cytokines and chemokines which are responsible for the inflammation of the joint. Continue reading
Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by various abnormalities, such as hypotonia, high body mass index (BMI), craniofacial anomalies, and obstructive sleep apnea. Anesthetic management of these patients requires special perioperative planning and care due to multisystem involvement. Continue reading
• LETTER FROM THE EDITORS
• KETOFOL (KETAMINE/PROPOFOL) AS A SUPERIOR SEDATIVE AGENT TO MITIGATE CARDIORESPIRATORY EFFECTS AND ALLEVIATE PAIN WHEN USED FOR PROCEDURAL SEDATION AND ANALGESIA: A REVIEW.
• POSTDURAL PUNCTURE HEADACHE: AN UPDATE ON TREATMENT IN OBSTETRIC PATIENTS.
• ΕΠΙΔΡΑΣΗ ΣΥΣΤΗΜΑΤΙΚΩΝ ΠΑΡΑΓΟΝΤΩΝ ΣΕ ΑΣΘΕΝΕΙΣ ΜΕ ΟΞΕΙΑ ΕΓΚΕΦΑΛΙΚΗ ΒΛΑΒΗ.
• THE WORK OF BREATHING DURING MECHANICAL VENTILATION IN A PORCINE MODEL OF ABDOMINAL HYPERTENSION:THE IMPACT OF SEPSIS.
• ANESTHETIC MANAGEMENT OF RENAL TRANSPLANTATION IN A PATIENT WITH ALPORT SYNDROME: A CASE REPORT. Continue reading
• KETOFOL (KETAMINE/PROPOFOL) AS A SUPERIOR SEDATIVE AGENT TO MITIGATE CARDIORESPIRATORY EFFECTS AND ALLEVIATE PAIN WHEN USED FOR PROCEDURAL SEDATION AND ANALGESIA: A REVIEW.
• POSTDURAL PUNCTURE HEADACHE: AN UPDATE ON TREATMENT IN OBSTETRIC PATIENTS.
• ΕΠΙΔΡΑΣΗ ΣΥΣΤΗΜΑΤΙΚΩΝ ΠΑΡΑΓΟΝΤΩΝ ΣΕ ΑΣΘΕΝΕΙΣ ΜΕ ΟΞΕΙΑ ΕΓΚΕΦΑΛΙΚΗ ΒΛΑΒΗ.
• THE WORK OF BREATHING DURING MECHANICAL VENTILATION IN A PORCINE MODEL OF ABDOMINAL HYPERTENSION:THE IMPACT OF SEPSIS.
• ANESTHETIC MANAGEMENT OF RENAL TRANSPLANTATION IN A PATIENT WITH ALPORT SYNDROME: A CASE REPORT. Continue reading
Dear colleagues,
The first issue of the Greek e-journal of Perioperative Medicine for 2023 presents a systematic review article of Papageorgiou L et al, in which the authors reviewed the existing evidence regarding superiority of ketofol (ketamine/propofol) in mitigating cardiorespiratory effects when administered as a main agent for procedural sedation and analgesia (PSA) in comparison to other drugs administered for such purposes underlying the safety and efficacy profile of this cocktail medication. They found limited evidence to support superiority of ketofol compared to other agents, specifically to propofol. They noted that the addition of ketamine to propofol in sub-dissociative doses is associated with less respiratory and haemodynamic complications during PSA, while achieving adequate analgesia and deeper sedation, possibly more amnesia and consequently high satisfaction in both patients and health-care professionals.
The next article of Varvarousi G et al was aimed to present the current knowledge on the treatment of postdural puncture headache (PDPH) in obstetric anesthesia practice, given to the fact that the incidence of accidental dural puncture complicating epidural cathether placement, in obstetric patients, varies between 0,13-0,91%.
The review article of Schizodimos Th et al described several systemic factors (arterial hypotension, low cardiac output, hypercapnia, hypocapnia, systemic hypoxia, anemia,… Continue reading
Procedural sedation and analgesia (PSA) is often necessary in order to deal with anxiety, pain and stress that may accompany patients at the hospital during invasive, unpleasant and/or painful procedures. The literature has not presented firm conclusions regarding ideal sedative agents in terms of efficacy and safety in PSA or even present firm data regarding superiority of specific drugs over others which are considered the “gold-standard” in sedation (i.e. propofol). Continue reading
Neuraxial analgesia and anaesthesia in an obstetric patient is associated with the risk of accidental dural puncture and subsequent development of a post dural puncture headache (PDPH). The management of accidental dural puncture requires consists of prevention of PDPH, patient’s information, early diagnosis, treatment, and monitoring until remission of PDPH. Continue reading
Η οξεία εγκεφαλική βλάβη (acute brain injury, ABI) αποτελεί συχνό κλινικό πρόβλημα, που απαιτεί άμεση και επείγουσα αντιμετώπιση. Περιλαμβάνει οποιαδήποτε πάθηση επηρεάζει οξέως το κεντρικό νευρικό σύστημα (ΚΝΣ), [π.χ. τραυματική εγκεφαλική βλάβη (traumatic brain injury, TBI)] και έχει δύο συστατικά, την πρωτογενή (primary brain injury, PBI) και τη δευτερογενή εγκεφαλική βλάβη (secondary brain injury, SBI)1. Continue reading
The work of breathing (WOB) is the amount of energy, which is consumed by the respiratory muscles, in order to perform one complete respiratory cycle. In several medical conditions, WOB might rise to a critical level which could necessitate initiation of mechanical ventilation (MV) or complicate weaning of the patient from MV. Continue reading
